House vacation rentals in Panama
Find and book unique houses on Airbnb
Top-rated house rentals in Panama
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Panama house rentals
House rentals with a pool
Home in Panama
Villa Isabella in Coronado Beach Panama
Home in Bajo Boquete
Secluded Riverfront Home - Boquete area with Pool
Home in contadora
villa in counter, pearls
Home in Panama City
Beautiful house with private pool
Home in Playa Mata Oscura
Casa De Ola, Jungle Beach Cabin
Home in Playa Venao
Casa Samambaia - sea view tropical paradise w pool
Home in San Carlos
Beach House-Ocean View Rooftop Jacuzzi & Pool
Home in Playa Bluff
Jungle House 100m from the beach
Weekly house rentals
Home in Bocas del Toro
La Casita Barrbra BnB
Home in Santa Catalina
Casa Colibrí - modern house in the green
Home in Nueva California
Spacious 3 bedroom house in Volcan cloud forest
Home in Bocas del Toro
Tropical Paradise, Oceanfront Home in the Jungle
Home in Panamá
Unique 4 room house - direct access to the beach
Home in La Guaira
Puntita Manzanillo, fantastic sea and jungle
Home in Bocas Del Toro
Wiona of Villa Paraiso | Beachfront Villa & Pool
Home in Boquete
Caturra Casita @ Finca Panda
Private house rentals
Home in David
Beautiful house in the heart of David.
Home in Bull Beach
Yellowfin Casa 3
Home in Río Hato
Poolside Paradise in Santa Clara
Home in Jaramillo Arriba
Spectacular House in Boquete w/King Beds & Hot Tub
Home in Bocas del Toro
Casa del Fuego - Caribbean Beachfront Magic!
Home in Bastimentos
Spacious, Over the Water Home with Plunge Pool
Home in Torio
Ideal Creative Retreat Immersed in Forest
Home in Bocas del Toro Province
The Pool House, Beach House on Paunch Beach
Destinations to explore
- Mansion rentals Panama
- Private suite rentals Panama
- Rentals with an accessible height bed Panama
- Cottage rentals Panama
- Rentals with a fireplace Panama
- Rentals with beach access Panama
- Rentals with a home theater Panama
- Monthly Rentals Panama
- Boutique hotel rentals Panama
- Rentals with breakfast Panama
- Smoking-friendly rentals Panama
- Chalet rentals Panama
- Bed and breakfasts Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Villa rentals Panama
- Hotel rentals Panama
- Nature eco lodge rentals Panama
- Pet-friendly rentals Panama
- Townhouse rentals Panama
- Loft rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Tiny house rentals Panama
- Condo rentals Panama
- Beach condo rentals Panama
- Rentals with a sauna Panama
- Rentals with a patio Panama
- Waterfront rentals Panama
- Island rentals Panama
- Vacation home rentals Panama
- Guesthouse rentals Panama
- Rentals with a washer and dryer Panama
- Treehouse rentals Panama
- Boat rentals Panama
- Farmstay rentals Panama
- Apartment rentals Panama
- Family-friendly rentals Panama
- Rentals with a firepit Panama
- Fitness-friendly rentals Panama
- Bungalow rentals Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Rentals with pools Panama
- Rentals with lake access Panama
- Kid-friendly rentals Panama
- Beach house rentals Panama
- Rentals with a hot tub Panama
- Wheelchair accessible rentals Panama
- House rentals Panama City
- Guesthouse rentals Panama City
- House rentals Playa Coronado
- House rentals Altos del Maria
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom