Hotel vacation rentals in Panama
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Top-rated hotels in Panama
Guests agree: these hotels are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Panama hotels
Family-friendly hotels
Nature lodge in Darién Province
La Chunga
Hotel room in PA
double room, island counter
Private room in Cébaco
Island Lodge Retreat Cebaco Sunrise/Cebaco Island
Hotel room in San Carlos
B) Beach, surf and Relax with King size bed
Hotel room in Alto Boquete
Cabañas Villa San Miguel #1 /Baja
Hotel room in Playa Morillo, Mariato
Double room IXORA with partial ocean view balcony
Private room in Santa Catalina
Beachfront - Private double bedroom
Private room in Boca del Drago
Boca del drago room ocean front
Hotels with a pool
Private room in Panamá
Relax Room
Hotel room in Panamá
Pool side, Family suite, two bedroom one bath.
Hotel room in Playa Coronado
My spot - Panamá
Private room in Panama City
El Puente
Private room in Playa Coronado
Private suite with pool view
Hotel room in Panamá
Grand International Hotel
Private room in Cañas
Standard Suite
Private room in Pueblo Nuevo
Welcome to the heart of the Panama Canal
Hotels with a patio
Casa particular in Penonomé
Cozy 1 br 1 bath apartment with free parking
Casa particular in Río Hato
Villa en Playa Blanca Resort Río Hato
Casa particular in Búcaro
Casa Pesca sin frontier
Private room in Boca Chica
LIVE WITH MONKEYS IN ISLA BOCA BRAVA (HAB.C)
Private room in Soná District
SkyRoom- Private Room with Shared Bathroom
Private room in Alto Boquete
La casita de Elenita - sextuple room
Private room in Rio Hato
Resort en la playa con Comidas, bebidas y piscinas
Private room in Contadora Island
Avani - Cozy Island Getaway
Destinations to explore
- Mansion rentals Panama
- Private suite rentals Panama
- Rentals with an accessible height bed Panama
- Cottage rentals Panama
- Rentals with a fireplace Panama
- Rentals with beach access Panama
- Rentals with a home theater Panama
- Monthly Rentals Panama
- Boutique hotel rentals Panama
- Rentals with breakfast Panama
- Smoking-friendly rentals Panama
- Chalet rentals Panama
- Bed and breakfasts Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Villa rentals Panama
- Nature eco lodge rentals Panama
- Pet-friendly rentals Panama
- Townhouse rentals Panama
- Loft rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Tiny house rentals Panama
- Condo rentals Panama
- Beach condo rentals Panama
- Rentals with a sauna Panama
- Rentals with a patio Panama
- Waterfront rentals Panama
- Island rentals Panama
- Vacation home rentals Panama
- Guesthouse rentals Panama
- Rentals with a washer and dryer Panama
- Treehouse rentals Panama
- Boat rentals Panama
- Farmstay rentals Panama
- Apartment rentals Panama
- Family-friendly rentals Panama
- Rentals with a firepit Panama
- Fitness-friendly rentals Panama
- Bungalow rentals Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Rentals with pools Panama
- Rentals with lake access Panama
- Kid-friendly rentals Panama
- Beach house rentals Panama
- Rentals with a hot tub Panama
- Wheelchair accessible rentals Panama
- House rentals Panama
- Hotel rentals Panama City
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom